右美托咪定联合臂丛神经阻滞在上肢手术中的临床效果分析

Effect analysis of dexmedetomidine combined with brachial plexus block in the upper limb operation

目的探讨右美托咪定联合臂丛神经阻滞在上肢手术中的临床效果。方法将我院收治的择期行上肢手术患者60例随机分为观察组和对照组,每组30例。观察组采用右美托咪定联合臂丛神经阻滞,对照组采用等量生理盐水泵注,对比两组患者不同时间点的镇痛效果、平均动脉压、心率和脉搏血氧饱和度的变化。结果两组患者麻醉前、臂丛阻滞后10min、静脉给药后5、10、30、60min及手术结束时SPO2的比较均无统计学意义(P>0.05);两组患者麻醉前、臂丛阻滞后10min、静脉给药后5min的MAP和HR的差异无统计学意义(P>0.05);观察组患者静脉给药后10、30、60min及手术结束时的MAP和HR值明显低于对照组(P<0.05)。结论右美托咪定联合臂丛神经阻滞对上肢手术患者的镇痛效果较好,安全性高,应广泛推广。

Objective To investigate the clinical effect of dexmedetomidine combined with brachial plexus block in upper limb operation.Methods A total of 60 cases of patients who will be elective upper limb operation were collected and randomly divided into observation group and control group,30 cases in each group.The patients in the observation group received dexmedetomidine combined with brachial plexus block,while those in the control group were treated with saline infusion.The analgesic effect,mean arterial pressure,heart rate and pulse oxygen saturation at the different time points were compared between the two groups.Results The oxygen saturation（SPO2）had no statistical significance between the two groups before anesthesia,10 min after brachial plexus block,5,10,30,60 min after intravenous administration and the end of the operation（P〉0.05）.The mean artery pressure（MAP）and Heart Rate（HR）were no significant differences between the two groups before anesthesia,10 min after brachial plexus block and 5min after intravenous administration（P〉0.05）.The MAP and HR were lower than that of control group at 10,30,60 min after intravenous administration and the end of the operation（P〈0.05）.Conclusion Dexmedetomidine combined with brachial plexus block has good analgesic effect and high safety in the upper limb operation,which is worthy of application.