嗜麦芽窄食单胞菌的抗感染治疗1例及文献复习

Anti-infection Treatment of Stenotrophomonas Maltophilia: A Case Report and Review of the Literature

目的为嗜麦芽窄食单胞菌的抗感染治疗提供方案,达到合理用药的目的。方法报道、分析1例案例,同时查阅相关文献进行综述讨论。结果患者使用头孢吡肟、亚胺培南西司他丁联合利奈唑胺治疗后,感染控制不理想,更换为头孢哌酮舒巴坦联合莫西沙星抗感染治疗,患者逐渐好转,检索相关研究并进行分析,该治疗方案是可行的。结论头孢哌酮舒巴坦联合莫西沙星治疗嗜麦芽窄食单胞菌感染疗效好、可行,但是否为最优方案有待进一步临床试验。

OBJECTIVE To provide an anti-infection therapeutic regimen of Stenotrophomonas maltophilia and promote rational administration. METHODS A case of anti-infection treatment of Stenotrophomonas Maltophilia was reported and analyzed. Relevant literature was reviewed. RESULTS By using cefepime, imipenem cilastatin combined with linezolid, the patient＇s infection was not well controlled. Later cefoperazone sulbactam combined with moxifloxacin was used, the patient gradually improved. The available literature suggested that this therapeutic regimen was feasible. CONCLUSION Using cefoperazone sulbactam combined with moxifloxacin has curative an effect on the infection of Stenotrophomonas maltophilia, but wheter it＇s optimal program is difficult to assess whether it is the optimal scheme needs further clinical experiments.