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结直肠癌患者淋巴结转移度和检出数与预后的关系研究 被引量:2

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摘要 目的 探讨结直肠癌患者淋巴结转移度和检出数与预后的关系,为临床干预提供参考.方法 选取2009年1月至2013年11月我院收治的行根治性切除手术治疗的结直肠癌患者134例作为研究对象.所有病例均具备完整的临床病理资料和随访记录,随访时间为5年,依据淋巴结阳性数目将N分期分为N1和N2,根据转移度分为四组.回顾性收集统计患者的一般临床资料及病理特征,并做统计学分析.结果 共有N1 93例和N2 41例;A组32例,B组37例,C组33例和D组32例.四组患者比较,患者的切除淋巴结检出数、阳性淋巴结检出数、血型、肿瘤类型和N分期组间差异有统计学意义(P<0.05).患者转移度与预后的单因素分析表明,患者的肿瘤位置、肠梗阻、血清CEA浓度、N分期、血型、淋巴结转移度、切除淋巴结检出数和阳性淋巴结检出数与患者的预后密切相关(P<0.001).随访患者60个月的无进展生存情况,结果表明A组生存率为46.33%,B组生存率为30.25%,C组生存率为22.57%,D组生存率为0%,组间比较差异有统计学意义(P<0.01).将相关变量进行Logistic回归分析,结果表明,血清CEA浓度、淋巴结转移度、切除淋巴结检出数和阳性淋巴结检出数是影响结直肠癌患者预后的独立危险因素(P<0.05).结论 结直肠癌患者淋巴结转移度和检出数与预后密切相关.
作者 林海晨 李喆
出处 《国际医药卫生导报》 2015年第20期2989-2992,共4页 International Medicine and Health Guidance News
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