齐多拉米双夫定片微生物检查方法研究

Methodological study on microbial limit test of Zidovudine and Lamivudine tablets

建立齐多拉米双夫定片微生物检查方法。方法取齐多拉米双夫定片,按《中国药典》2010版二部附录所载的"微生物限度检查法"项下方法试验,结果表明:采用薄膜过滤法测定细菌数,平皿法测定霉菌和酵母菌数,薄膜过滤法检查控制菌大肠埃希菌。

According to the Chinese pharmacopieia （ 2010 Edition ） , an accurate method for microbial limit test of Zidovudine and Lamivudine tablets was established in this study.Membrane filtration and/or direct plate culture were taken for counting bacteria, mold and yeast using E.coli as the controls.