三维超声检测子宫内膜容积预测冻融胚胎移植结局

Prediction of frozen- thawed embryo transfer outcome by detection of endometrial volume via three- dimensional ultrasound

目的探讨三维超声检测子宫内膜容积对冻融胚胎移植结局的预测价值。方法选取行冻融胚胎移植的患者296例,选择自然周期、促排卵、人工周期子宫内膜准备方案,在冻融胚胎移植当天以三维超声测定子宫内膜容积,并对患者妊娠结局进行预测。结果本研究患者共妊娠124例,非妊娠172例,妊娠组和非妊娠组患者一般资料差异无统计学意义(P>0.05);不同准备方法的妊娠组与非妊娠组患者子宫内膜厚度差异无统计学意义(P>0.05);妊娠组患者子宫内膜容积均明显高于非妊娠组(P<0.05)。结论三维超声检测子宫内膜容积是作为冻融胚胎移植妊娠结局预测的有效指标,同时具有无创、快速以及准确的优点,适合临床推广应用。

Objective To explore the value of detection of endometrial volume via three-dimensional ultrasound for predicting fro- zen-thawed embryo transfer （FET） outcome. Methods A total of 296 patients receiving FET were selected, natural cycle, ovulation induction, and artificial cycle endometrial preparation program were chosen, three-dimensional ultrasound was used to detect endometrial volume patients were non-pregnant, there was no statistically significant difference in the general information between pregnancy group and non-pregnancy group （P〉0. 05 ） ; there was no statistically significant difference in endometrial thickness among the patients receiving different preparing methods in pregnancy group and non-pregnancy group （P〉0.05） ; endometrial volume in pregnancy group was statistically signifi- cantly higher than that in non-pregnancy group （P〈0. 05） . Conclusion Detecting endometrial volume via three-dimensional ultrasound is an effective indicator to predict pregnancy outcome of patients receiving FET, which has the advantages of non-invasion, quickness, and accuracy, the method is suitable for clinical promotion and application.