支气管激发试验对咳嗽变异性哮喘的诊断价值

Diagnostic value of bronchial provocation test in cough variant asthma

目的探讨支气管激发试验对咳嗽变异性哮喘的诊断价值。方法对286例慢性咳嗽患者进行肺功能及乙酰甲胆碱支气管激发试验,统计支气管激发试验阳性率及阳性患者中咳嗽变异性哮喘的诊断率。结果支气管激发试验前,本组286例肺功能检测FEV1/FVC均≥70%,均成功完成支气管激发试验。其中激发试验阳性138例(48.3%)。激发试验阳性者中,经临床治疗反应及进一步检查确诊咳嗽变异性哮喘132例(95.7%)。结论对慢性咳嗽患者进行支气管激发试验,有助于咳嗽变异性哮喘的早期诊断。

Objective To explore the diagnostic value of bronchial provocation test in cough variant asthma. Methods 286 patients with chronic cough received lung function and methacholine bronchial provocation test. The positive rate of bronchial provocation test and the diagnosis rate of cough variant asthma in the positive patients were calculated. Results Before the test, the FEV1/FVC in the lung function test for all the patients were ≥70%. The bronchial provocation tests were completed successfully.There were 138 cases（48.3%） of positive bronchial provocation test. Among the positive cases, 132 patients（95.7%） were diagnosed as cough variant asthma according to the clinical therapeutic reaction and by further examination. Conclusion The bronchial provocation test for patients with chronic cough is helpful to the early diagnosis of cough variant asthma.