获得性免疫缺陷综合征弓形体脑炎DWI分析

Analyses of DWI characteristics ofacquired immunodeficiency syndrome concomitant with focal toxoplasmic encephalitis

目的探讨获得性免疫缺陷综合征(AIDS)弓形虫脑炎的磁共振扩散加权成像(DWI)的特点。方法观察分析我院确诊为AIDS相关性弓形虫脑炎的11例患者磁共振扩散加权成像的特点。结果 AIDS相关性弓形虫脑炎病灶坏死区、实性区、水肿区与对照区(对侧相应正常区域)ADC值分析比较:病灶水肿区与对照区的差异有统计学意义(P<0.05)。结论 ADC值的检测有助于病灶的分期及治疗后的疗效评价,但其绝对值不能作为弓形体脑炎诊断的明确依据。

Objective To investigate the diffusion weighted imaging （DWI） features of AIDS concomitant with toxoplas- ma encephalitis. Methods Analyses of DWI characteristics of 11 patients diagnosed with AIDS concomitant with toxoplasma encephalitis were performed in this work. Results The mean ADC values of focal necrotic area, solid cellular regions, and contralateral normal area were measured. Statistical analysis showed there existed a significant difference between contralateral normal tissue and edema area. Conclusion DWI sequences he helpful for the encephalitis staging and efficiency evaluation. But the absolute ADC value of the lesion can not be used as the accurate diagnostic basis for toxoplasma encephalitis.