全髋关节置换术后感染的危险因素分析

Analysis of Infection Risk Factors after Total Hip Replacement

目的探讨全髋关节置换术后感染的危险因素。方法回顾性分析85例全髋关节置换术患者的临床资料。结果全髋关节置换术后感染发生率为5.88%(5/85),单因素分析结果显示,年龄≥60岁,手术时间≥160 min,引流时间≥2d,长期应用激素,合并糖尿病,具有髋关节手术史,血清清蛋白<35 g/L者全髋关节置换术后感染率明显增高(P<0.05),而不同性别与全髋关节置换术后感染无明显相关性(P>0.05),全髋关节置换术后感染的多因素Logistics回归分析显示,长期应用激素、合并糖尿病与髋关节手术史是全髋关节置换术后感染的独立危险因素(OR=6.541、6.312、6.401,均P<0.05)。结论全髋关节置换术后感染与多种临床因素具有明显相关性,根据多种危险因素采用积极预防与早期临床干预措施降低全髋关节置换术后感染发生风险。

Objective To explore the risk factors of infection after total hip replacement. Methods Clinical data of 85 cases of patients with total hip replacement were retrospectively analyzed. Results The infection rate after total hip replacement was 5.88% （5/85）. After total hip replacement, single factor analysis showed that patients with an obvious high infection rate had the following characteristics ： age ≥ 60, operation time ≥ 160 rain, drainage time 〉t 2 d, long - term use of hormone, combined diabetes, history of hip joint surgery and Serum albumin 〈 35 g/L. Gender difference had no obvious correlation with infection after total hip replacement （ P 〉 0.05 ）. Multiple factor analysis showed that long - term use of hormones, combined diabetes and history of hip joint surgery were independent risk factors for infection （ OR = 6. 541, 6. 312, 6. 401, P 〈 0. 05 ）. Conclusion Considering the fact that infection after total hip replacement is significantly correlated with many clinical factors, active prevention and early clinical intervention measures should be implemented to reduce the risk of infection after total hip replacement accordingly.