氨溴索联合特布他林雾化吸入治疗慢性支气管炎急性发作的临床观察

Effect of Atomization Inhalation of Ambroxol Combined with Terbutaline on Chronic Bronchitis

目的探讨氨溴索与特布他林联合雾化吸入治疗慢性支气管炎急性发作的疗效及安全性。方法将我院收治96例慢性支气管炎急性发作期患者分为两组:对照组48例和观察组48例。对照组采用常规治疗方案,观察组在此基础上加用氨溴索与特布他林联合雾化吸入。结果观察组治疗显效率和总有效率均明显高于对照组(P<0.05);观察组临床症状获得改善时间均明显短于对照组(P<0.05);观察组血气分析指标改善优于对照组(P<0.05);两组不良反应发生率无明显差异(P>0.05)。结论氨溴索与特布他林联合雾化吸入治疗慢性支气管炎急性发作可取得较常规治疗方法更为显著的临床疗效,且安全性好。

Objective To investigate the curative effect and safety of atomization inhalation therapy of combined use of ambroxol and terbutaline on chronic bronchitis. Methods 96 chronic bronchitis patients with acute exacerbation in our hospital were divided in- to two groups ： 48 cases included in control group and the other 48 cases in the observation group. The control group was treated with conventional therapy while the observation group was treated, besides the conventional therapy, with the combination of ambroxol and terbutaline inhalation. Results The effective rate and total effective rate of the observation group was significantly higher than the con- trol group （ P 〈 O. 05 ）, improving time of clinical symptoms in observation was significantly shorter than that of the control group （ P 〈 0. 05 ）, blood gas analysis was better in the observation group than the control group （P 〈 0. 05 ）, there was no significant difference in adverse reactions （P 〉 0. 05）. Conclusion The combination use of Ambroxol and terbutaline inhalation for acute chronic bronchitis can achieve significant clinical efficacy and safety compared with conventional treatment methods.