曲安奈德与利多卡因局部封闭治疗跟骨骨质增生症的效果观察

Observation of Efficacy of Triamcinolone Acetonide and Lidocaine in Partial Closure Treatment of Calcaneal Bone Hyperplasia

目的探讨曲安奈德与利多卡因局部封闭治疗跟骨骨质增生症的效果。方法选取2012年6月至2013年6月我院收治的96例跟骨骨质增生症患者,随机分为对照组与观察组,每组48例,对照组给予25 mg泼尼松龙和1 m L 2%的利多卡因进行局部痛点注射,观察组给予40 mg曲安奈德和1 m L 2%的利多卡因进行局部痛点注射,治疗4 w后比较两组患者的临床疗效、AOFAS踝-后足评分。随访1年后,比较两组患者的复发率。结果治疗后,观察组的治疗总有效率(94.6%)高于对照组(81.8%),具有统计学差异(P<0.05);两组患者治疗后AOFAS踝-后足疼痛、功能、总分均高于治疗前,具有统计学差异(P<0.05);且观察组治疗后AOFAS踝-后足疼痛、功能、总分均高于对照组,具有统计学差异(P<0.05);随访1年,观察组复发率为5.4%,对照组为7.3%,两组患者复发率不具有统计学差异(P>0.05)。结论曲安奈德与利多卡因局部封闭治疗跟骨骨质增生症的临床疗效较好,可缓解跟骨骨质增生症患者的疼痛,复发率较低,值得在临床上推广使用。

Objective To explore the efficacy of Triamcinolone acetonide and lidocaine in partial closure treatment of calcaneal bone hyperplasia. Methods 96 patients with ealeaneal bone hyperplasia were randomly divided into the control group and the observa- tion group from June 2012 to June 2013 in our hospital, with 48 cases in each group. Patients in the control group were treated with 25mg prednisolone and 1 mL 2% lidocaine topical pain point injection, while those in the observation group were treated with 40mg tri- amcinolone acetonide and I ml 2% lidocaine topical pain point injection treatment. After 4 weeks of treatment, clinical efficacy and AOFAS ankle hind foot score of the two groups were compared. After one year of follow - up, recurrence rate of the two groups were compared. Results After treatment, total effective rate of the observation group （94. 6% ） was higher than that of the control group （81.8%） , with statistically significant difference （P 〈 O. 05 ）. After treatment, AOFAS ankle hind foot pain score, function score and total score of the two groups were higher than before treatment, with statistically significant difference （ P 〈 0. 05 ）. AOFAS ankle hind foot pain, function and scores of the observation group were higher than those of the control group, which was statistically significant （ P 〈 0. 05 ）. After 1 year of follow - up, recurrence rate of the observation group was 5.4%, while that of the control group was 7.3%, which was not statistically significant （ P 〉 O. 05 ）. Condusion Triamcinolone acetonide and lidocaine partial closure treatment has good effect, low recurrence rate and sound pain relief effect in the treatment of calcaneal bone hyperplasia, which is worthy to be intro- duced in clinical practice.