青少年超重/肥胖与肠易激综合征相关性研究

Relationship between high body mass index and irritable bowel syndrome in Chinese adolescents

目的初探青少年超重/肥胖与肠易激综合征(IBS)之间的相关性。方法随机选取初中及高中学生,测量身高、体质量,并填写IBS流行病学调查表。结果入选1 173名中学生,初中生700名,高中生473名;超重/肥胖的总检出率30.52%。男生中超重/肥胖检出率(28.40%)与女生(32.65%)的差异无统计学意义(P=0.114);初中生超重/肥胖检出率(30.57%)与高中生(30.44%)的差异也无统计学意义(P=0.963)。221名学生患有IBS,检出率为18.84%。男生IBS检出率(17.00%)与女生(20.68%)的差异无统计学意义(P=0.107);高中生IBS检出率(26.85%)高于初中生(13.43%),差异有统计学意义(P=0.000);超重/肥胖学生IBS检出率(22.07%)与正常体质量学生(17.42%)的差异无统计学意义(P=0.061);超重/肥胖与正常体质量学生之间IBS亚型的分布差异也无统计学意义(χ2=0.91,P=0.823)。结论超重/肥胖与IBS是青少年的常见病,但两者之间相关性还有待证实。

Objectives To explore the impact of high body mass index（BMI） on irritable bowel syndrome（IBS） in Chinese adolescents. Methods The students were randomly selected from middle school and high school. They completed the epidemiological questionnaire of IBS and had their height, body mass measured. Results In total, 1173 students were recruited, including 700 middle school students and 473 high school students. The incidence of overweight/obesity was 30.52%. The incidence of overweight/obesity was not significantly different between boys（28.40%） and girls（32.65%）（P=0.114）, and there was not significantly different between students from middle school（30.57%） and high school（30.44%）（P=0.963）. Two hundreds and twenty-one students suffered from IBS and the incidence of IBS was 18.84% with no significant gender difference. The incidence of IBS was significantly higher in students from middle school（13.43%） than those from high school（26.85%）（P〈0.001）. The incidence of IBS was not statistically significant between overweight/obese students（22.07%） and normal weight students（17.42%）（P=0.061）. The distribution of IBS subtypes had no statistical significance between overweight/obese and normal weight students（χ2=0.91,P=0.823）. Conclusions Overweight/obesity and IBS were extremely prevalent in Chinese adolescents, but the correlation between them remains to be confirmed.