脱去含氮芳香杂环中N-取代苄基的一种新方法

A New Method of N-Debenzylation of Nitrogen Aromatic Heterocyclic Compounds

O2环境下,N-取代苄基咔唑（或N-取代苄基吲哚）与叔丁醇钾反应可脱去苄基制得咔唑（或吲哚）,收率68%-94%或75%-89%,其结构经1H NMR和13C NMR确证。

The reaction of N-substituted benzylcarbazoles（ or N-substituted benzylindoles） with potassium tert-butoxide resulted in debenzylation to carbazole（ or indole） in oxygen. The yields were 68% -94%（ or 75% - 89%）. The structures were confirmed by1 H NMR and13 C NMR.