痰湿型多囊卵巢综合征月经异常与性激素水平相关性的研究

Research on the Correlation between Abnormal Menstrual Polycystic Ovary Syndrome of Phlegmy Wet and Sex Hormone Levels

目的探讨多囊卵巢综合征月经异常情况与性激素水平的相关性。方法将78例多囊卵巢综合征患者分为继发闭经组(37例)和月经稀发组(41例),测定其性激素促卵泡生成素(FSH)、促黄体生成素(LH)、孕酮(P)、睾酮(T)、血清泌乳素(PRL)、雌二醇(E2)水平,对比两组患者早卵泡期或闭经状态下各项性激素及体重指数、腰臀比值。结果痰湿型PCOS患者中,继发闭经组的血清T值显著高于月经稀发组(P<0.05);两组患者体重指数均值都大于25,达到Ⅰ度肥胖程度。两组患者腰臀比值均值超过0.85,表现为腹部脂肪堆积;继发闭经组月经改变时间明显长于月经稀发组(P<0.05)。结论痰湿型PCOS患者月经异常程度与雄激素水平有相关性;痰湿型PCOS患者中,继发闭经和月经稀发都易出现腹部肥胖,但两组患者体重指数和腰臀比值没有明显差异。

Objective To explore the correlation between abnormal menstrual polycystic ovary syndrome of phlegmy wet and sex hormone levels. Methods 78 cases of patients with polycystic ovary syndrome were divided into secondary amenorrhea group（ 37 cases） and oligomenorrhea group（ 41 cases）. The sex hormones follicle stimulating hormone（ FSH）, luteinizing hormone（ LH）, progesterone（P）, testosterone（T）, serum prolactin（PRL） and estradiol（E2） levels were determined, and the early follicular phase or amenorrhoea condition of various hormones, body mass index and waist-hip ratio of the two groups were compared. Results The serum T values of secondary amenorrhea group was significantly higher than that of the oligomenorrhea group（P〈0.05）. The body mass index of the two groups was greater than 25, and achevedⅠdegree of obesity. The mean waist-hip ratio of the two groups more than 0.85, which showed the accumulation of abdominal fat. Conclusion There was correlation between abnormal menstrual of phlegmy wet polycystic ovary syndrome and sex hormone levels. In patients with abnormal menstrual polycystic ovary syndrome of phlegmy wet, secondary amenorrhea patients and menstrual oligomenorrhea patients were easy to appear abdominal obesity, but the body mass index and waist-hip ratio of the two groups had no obvious difference.