肠坦液保留灌肠预防急性放射性直肠损伤42例

Forty-Two Cases with Acute Radiation Rectal Injury Prevented with Retention Enema of Changtan Liquid

目的:观察肠坦液保留灌肠预防急性放射性直肠损伤的临床效果。方法:选取急性放射性直肠损伤患者86例,随机分成对照组和观察组,每组42例。对照组给予常规预防治疗,观察组在对照组治疗的基础上加用肠坦液保留灌肠治疗。结果:对照组有效率59.52%,观察组有效率92.86%,两组比较差异有统计学意义(P<0.05);对照组药物应用率为21.42%,观察组药物应用率为4.76%,两组比较差异也有统计学意义(P<0.05)。结论:肠坦液保留灌肠能减少急性放射性直肠损伤发生率,提高临床疗效。

Objective： To observe the clinical preventive effects of retention enema of Changtan Liquid on acute radiation rectal injury. Methods： 86 cases with acute radiation rectal injury were randomized into control group and observation group,with 42 cases in each group. Control group were given routine preventive treatment while observation group were added with retention enema of Changtan Liquid. Results： The effective rate was 59. 52% in control group and 93. 18% in observation group; the difference had statistical significance（ P 〈0. 05）. The occurrence rate of drug application was 21. 42% in control group and 4. 54% in observation group; the difference had statistical significance（ P 〈0. 05）. Conclusion： Retention enema of Changtan Liquid can reduce the occurrence rate of acute radiation rectal injury and improve the clinical therapeutic effects.