期刊文献+

冠状动脉球囊损伤后管壁原癌基因c-myc表达的变化 被引量:2

Significance of c-myc mRNA expression in the coronary artery after balloon injury in a swine model
下载PDF
导出
摘要 目的 :探讨原癌基因c-myc的表达与冠状动脉球囊损伤后内膜增殖的关系。方法 :建立猪的冠状动脉球囊损伤模型 ,观察形态学变化 ,并用RT -PCR的方法检测损伤冠状动脉壁内c-mycmRNA的表达。结果 :冠状动脉球囊损伤后 6周管壁内膜明显增生 ,管腔狭窄 ,c-mycmRNA的相对表达强度明显高于正常冠状动脉壁。结论
出处 《中国病理生理杂志》 CAS CSCD 北大核心 2002年第8期992-993,共2页 Chinese Journal of Pathophysiology
  • 相关文献

参考文献4

  • 1Bartling B,Hoffmann J,Holtz J,et al.Quantification of cardioprotective gene expression in porcine short-term hibernating myocardium[].Journal of Molecular and Cellular Cardiology.1999
  • 2Dindy MS,Sonenshin GD.Regulation of oncogene expression in cultured aortic smooth muscle cells: post- transcriptional control of c -myc mRNA[].Journal of Biological Chemistry.1986
  • 3Campan M,Desgranges C,Gadeau AP,et al.Cell cycle dependent gene expression in quiescent stimulated and asynchronously cycling arterial smooth muscle cells in culture[].Journal of Cellular Physiology.1992
  • 4Miano J,Vlasic N,Robert R,et al.Smooth muscle cell injury[].Arteriosclerosis and Thrombosis.1993

同被引文献18

  • 1徐列明 刘成 等.一种稳定和高产的肝贮脂细胞分离法[J].细胞生物学杂志,1995,17:143-143.
  • 2Li D, Friedman SL. Liver fibrogenesis and the role of hepatic stellate cell: New insights and prospects for therapy [ J ]. J Gastroenterol Hepatol, 1999, 14(7):618-633.
  • 3Thempson CB, Challoner P, Neiman PE, et al. Expression of c - fos, the c - myh proto - oncogene during cellular proliferation[J]. Nature, 1986,319(6052):374- 380.
  • 4Oh IH, Reddy EP. The myb gene family in cell growth, differentiation, and apoptosis[J]. Oncogene, 1999, 18(19):3017- 3033.
  • 5Kitada T, Seki S, Nakatani K, et al. Hepatic expression of c- myb in chronic human liver disease [ J ]. Hepatology,1996,26(6) : 1506 - 1512.
  • 6Tappero G, Farina M, Negro F, et al. Intrahepatic expression of c - fos, c - myb and oncogenes: correlation with virus - in-duced chronic liver disease and response to interferon[J]. Ital J Gastroenterol, Hepatol, 1997,29(2) : 148 - 154.
  • 7Afroze T, Husain M. c- myb- binding sites mediate G1/S-associated repression of the plasma membrane Ca^2+ - ATPase- 1 promoter [ J ]. J Biol Chem, 2000, 275 (12) : 9062 -9069.
  • 8Pinzani M, Marra F, Carloni V. Signal transduction in hepatic stellate cells[J]. Liver, 1998, 18(1):2- 13.
  • 9Ebinuma H, Saito H, Saito Y, et al. Antisense oligodeoxynucleotide against c-myc mRNA induces differentiation of human hepatocellular carcinoma cells[J]. Int J Oncol, 1999, 15(5): 991-999.
  • 10Bennett MR, Anglin S, McEwan JR, et al. Inhibition of vascular smooth muscle cell proliferation in vitro and in vivo by c-myc. antisense oligodeoxynucleotides[J]. J Clin Invest, 1994, 93(2): 820-828.

引证文献2

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部