冠状动脉球囊损伤后管壁原癌基因c-myc表达的变化
被引量:2
Significance of c-myc mRNA expression in the coronary artery after balloon injury in a swine model
摘要
目的 :探讨原癌基因c-myc的表达与冠状动脉球囊损伤后内膜增殖的关系。方法 :建立猪的冠状动脉球囊损伤模型 ,观察形态学变化 ,并用RT -PCR的方法检测损伤冠状动脉壁内c-mycmRNA的表达。结果 :冠状动脉球囊损伤后 6周管壁内膜明显增生 ,管腔狭窄 ,c-mycmRNA的相对表达强度明显高于正常冠状动脉壁。结论
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
2002年第8期992-993,共2页
Chinese Journal of Pathophysiology
参考文献4
-
1Bartling B,Hoffmann J,Holtz J,et al.Quantification of cardioprotective gene expression in porcine short-term hibernating myocardium[].Journal of Molecular and Cellular Cardiology.1999
-
2Dindy MS,Sonenshin GD.Regulation of oncogene expression in cultured aortic smooth muscle cells: post- transcriptional control of c -myc mRNA[].Journal of Biological Chemistry.1986
-
3Campan M,Desgranges C,Gadeau AP,et al.Cell cycle dependent gene expression in quiescent stimulated and asynchronously cycling arterial smooth muscle cells in culture[].Journal of Cellular Physiology.1992
-
4Miano J,Vlasic N,Robert R,et al.Smooth muscle cell injury[].Arteriosclerosis and Thrombosis.1993
同被引文献18
-
1徐列明 刘成 等.一种稳定和高产的肝贮脂细胞分离法[J].细胞生物学杂志,1995,17:143-143.
-
2Li D, Friedman SL. Liver fibrogenesis and the role of hepatic stellate cell: New insights and prospects for therapy [ J ]. J Gastroenterol Hepatol, 1999, 14(7):618-633.
-
3Thempson CB, Challoner P, Neiman PE, et al. Expression of c - fos, the c - myh proto - oncogene during cellular proliferation[J]. Nature, 1986,319(6052):374- 380.
-
4Oh IH, Reddy EP. The myb gene family in cell growth, differentiation, and apoptosis[J]. Oncogene, 1999, 18(19):3017- 3033.
-
5Kitada T, Seki S, Nakatani K, et al. Hepatic expression of c- myb in chronic human liver disease [ J ]. Hepatology,1996,26(6) : 1506 - 1512.
-
6Tappero G, Farina M, Negro F, et al. Intrahepatic expression of c - fos, c - myb and oncogenes: correlation with virus - in-duced chronic liver disease and response to interferon[J]. Ital J Gastroenterol, Hepatol, 1997,29(2) : 148 - 154.
-
7Afroze T, Husain M. c- myb- binding sites mediate G1/S-associated repression of the plasma membrane Ca^2+ - ATPase- 1 promoter [ J ]. J Biol Chem, 2000, 275 (12) : 9062 -9069.
-
8Pinzani M, Marra F, Carloni V. Signal transduction in hepatic stellate cells[J]. Liver, 1998, 18(1):2- 13.
-
9Ebinuma H, Saito H, Saito Y, et al. Antisense oligodeoxynucleotide against c-myc mRNA induces differentiation of human hepatocellular carcinoma cells[J]. Int J Oncol, 1999, 15(5): 991-999.
-
10Bennett MR, Anglin S, McEwan JR, et al. Inhibition of vascular smooth muscle cell proliferation in vitro and in vivo by c-myc. antisense oligodeoxynucleotides[J]. J Clin Invest, 1994, 93(2): 820-828.
引证文献2
-
1马会慧,姚集鲁,姚春斓,李刚,陈雪娟,顾琳,杨绍基.逆转录病毒介导的反义c-myb对肝星状细胞增殖及Ⅰ型胶原基因表达的影响[J].中国病理生理杂志,2003,19(6):726-729. 被引量:3
-
2刘颖格,戚好文,李焕章,苏明权,于文彬,马越云.反义c-myc寡核苷酸抑制大鼠胸腺淋巴细胞增殖[J].中国病理生理杂志,2004,20(5):745-747.
二级引证文献3
-
1黄文勇,曾骏文,刘奕志,吴明星.儿茶素抑制兔晶状体上皮细胞增殖[J].中国病理生理杂志,2005,21(12):2443-2446. 被引量:4
-
2杨雅丽,韩跃武.PDGF-B反义寡脱氧核苷酸对大鼠肝星状细胞增殖及Ⅰ型胶原合成的影响[J].中国病理生理杂志,2008,24(3):582-585. 被引量:6
-
3凌云彪,许瑞云,邱万寿,褚中华,杨宏志,谈智,区庆嘉.大鼠含抗肝纤维化中药的血清对肝星状细胞的作用[J].中国病理生理杂志,2003,19(12):1649-1652. 被引量:5
-
1朱智明,刘伊丽,翟文生,万华印,唐志宏,宾建平.离体人冠状动脉球囊损伤后血小板沉积量的实验研究[J].第一军医大学学报,1995,15(2):147-148. 被引量:1
-
2文应峰,盖鲁粤,张端珍,曾永寿.^(32)P液体充盈球囊照射预防猪冠状动脉球囊损伤后细胞增殖和内膜增生[J].解放军医学杂志,2001,26(5):339-341.
-
3何昆仑,文应峰,高焱章,陈练,盖鲁粤,黄大显,王所亭.血管内放射抑制猪冠状动脉球囊损伤后血管重塑的机制[J].军医进修学院学报,2000,21(3):223-225.
-
4何昆仑,盖鲁粤,黄大显,王所亭,郭爱桃,高焱章.血管内放射对猪冠状动脉球囊损伤后细胞增殖和凋亡的影响[J].解放军医学杂志,1999,24(6):423-425.
-
5高杨,邓江,黄燮南.人参皂苷Rg1对大鼠血管球囊损伤后原癌基因c-myc表达的影响[J].遵义医学院学报,2012,35(1):6-8. 被引量:1
-
6瞿利军,郑新民,李世文,胡礼泉.Fas、FasL和C-myc基因表达与隐睾生殖细胞凋亡的关系[J].中华泌尿外科杂志,2002,23(12):727-727. 被引量:1
-
7袁向珍,张越,曹中朝,包秋红.卡维地洛对大鼠颈动脉损伤后VSMCs迁移和增殖的影响[J].内蒙古医学杂志,2015,47(1):1-4.
-
8谈梦伟,廖威麟,唐昊,陆方林,韩林,徐志云.人主动脉夹层组织Myc associated factor X的表达及其生物学功能[J].第二军医大学学报,2015,36(9):943-946.
-
9李聚敏,周焕芝,张五星,赵学伟.钙性尿毒症性小动脉病2例[J].中国血液净化,2014,13(9):676-676. 被引量:1
-
10龙明智,陈磊磊,杨季明,王迪斌,洪梅.姜黄素抗炎抗氧化作用与血管损伤后内膜增生[J].江苏医药,2003,29(10):735-737. 被引量:7