川东獐牙菜化学成分研究

STUDIES ON THE CHEMICAL CONSTITUENTS OF SWERTIA DAVIDA FRANCH

目的 研究川东獐牙菜 (SwertiadavidiFranch)活性成分。方法 用硅胶色谱技术分离化学成分 ,用UV ,IR ,NMR和MS等光谱方法鉴定化合物。结果 得到 3个化合物 ,分别鉴定为 :1,7 二羟基 3,8 二甲氧基酮 (V) ;1,8 二羟基 3,7 二甲氧基酮 (VI)和 1,8 二羟基 3,4 ,7 三甲氧基酮 (VII)。结论 VII为新酮 ,其余两个酮均首次从该植物中分离得到。

AIM To study the active constituents of Swertia davidi Franch.. METHODS Chromatography was used to isolate and purify the chemical components, their structures were identified by spectral analysis. RESULTS Three compounds were identified as 1,7 dihydroxy 3,8 dimethoxyxanthone (gentiacaulein) (V), 1,8 dihydroxy 3,7 dimethoxyxanthone (methylswertianin) (VI) and 1,8 dihydroxy 3,4,7 trimethoxyxanthone (VII). CONCLUSION Compound VII is a novel xanthone, named daviditin A, the others were isolated from Swertia davidi Franch. for the first time.