胃癌卵巢转移临床治疗决策

Clinical therapeutic strategies in the treatment of gastric cancer ovarian metastasis

胃癌卵巢转移又称Krukenberg瘤,临床并不少见,好发于30~49岁绝经前女性,预后差,是女性胃癌治疗中的难点和困惑。胃癌卵巢转移最可能的发病机制为胃肠道肿瘤的逆行性淋巴道转移。诊断的要点为单侧或双侧卵巢肿瘤结合有胃肠道肿瘤病史。外科治疗以根治性切除原发灶和转移灶为主,化疗可能使病人获得一定的疗效。

The ovarian metastatic tumor from gastric cancer is also called Krukenberg tumor, which is not rare in the clinic. It usually occurred in premenopausal women from 30 to 49 years old with poor prognosis and is the difficulty and confusion in the treatment of female gastric cancer. Currently, the most likely mechanism of Krukenberg tumor development is via retrograde lymphatic spreading from gastrointestinal cancers. The key points in the diagnosis of Krukenberg tumor are history of gastrointestinal cancers combined with unilateral or bilateral solid ovarian tumors. Radical excision of the primary and metastatic tumor is the reasonable choice. Patients with Krukenberg tumor may benefit from adjuvant chemotherapy.