膀胱炎性肌纤维母细胞瘤的研究进展

Research Progress of Inflammatory Myofibroblastic Tumor of the Bladder

膀胱炎性肌纤维母细胞瘤是一种少见的交界性膀胱软组织真性肿瘤,临床表现及术前影像学检查常提示膀胱恶性肿瘤,易误诊而导致膀胱全切,常需根据术后病理检查及免疫组织化学检查进行确诊。目前主要治疗方式为膀胱部分切除或经尿道膀胱肿瘤电切术,且术后不需要常规膀胱灌注化疗,大部分预后良好,少数可复发、转移。近年来对膀胱炎性肌纤维母细胞瘤的报道及研究逐渐增多,本文将从膀胱炎性肌纤维母细胞瘤的临床表现、影像学、病理特征以及发病机制及预后等方面进行综述。

Inflammatory myofibroblastic tumor of bladder is a rare true soft tissue tumor,which belongs to boundary type. Clinical manifestations and preoperative imaging findings often indicate the malignant tumor of urinary bladder,which even leads to radical cystectomy because of misdiagnosis. Definitive diagnosis often refers to postoperative pathological examination and immunohistochemistry examination. At present,partial cystectomy and transurethral electrocision of bladder tumor are preferred treatment methods. It is mostly believed that routine intravesical chemotherapy is not necessary after these two kinds of surgeries. Most patients undergoing the two kinds of surgeries have favorable prognosis,and a few will have relapse and transfer.The reports about inflammatory myofibroblastic tumor of bladder are increasing in recent years. This paper will review the clinical manifestation,imaging and pathological features, pathogenesis and prognosis about inflammatory myofibroblastic tumor of bladder.