C-反应蛋白检测在儿童社区获得性肺炎中的临床应用

Clinical significance of CRP detection for the Diagnosis of community-acquired pneumonia for children

目的分析社区获得性肺炎(CAP)儿童血清感染标志物C-反应蛋白(CRP)水平的改变,并探讨其临床意义。方法将115 CAP儿童分为细菌感染和支原体感染2组,于治疗前和治疗后分别在日立7600-010型全自动生化分析仪上采用比浊法检测血清CRP水平,并进行对照。结果细菌感染组较支原体感染组血清CRP水平明显升高(P<0.05);经过治疗,2组血清CRP水平均明显降低(P<0.05)。结论血清CRP水平有助于初步判断CAP的致病微生物,进而指导治疗;而动态观察血清CRP水平变化,有助于疗效判断,进而指导疗程的长短,是临床实用而简便的指标。

Objective To explore the clinical analysis determination of serum c-reaction protein （CRP）level with community-acquired pneumonia （CAP）in children. Methods The serum CRP level were analyzed in 52 pediatrics patients with bacterial pneumonia respectively and 63 with myeoplasma pneumonia respeetively.SPSS13.0 was used to analysis the differences between groups. Results The results indicated that the CRP level in children with bacterial pneumonia was higher than those with mycoplasma pneumonia （P〈0.05）.In after therapy,the serum CRP level in 115 pediatrics patients with bacterial pneumonia or myeoplasma pneumonia were discovered to normal levels （P〈0.05）. Conclusion The serum CRP level in children with bacterial pneumonia or mycoplasma pneumonia can be used clinical diagnosis, can be used the progresis of the disease.