宣肺清热合剂质量标准的建立

Establishment of quality standard of Xuanfeiqingre mixture

目的建立宣肺清热合剂的质量标准。方法采用薄层色谱法对宣肺清热合剂中枳壳和桑白皮进行定性鉴别。采用高效液相色谱法对制剂中黄芩苷进行定量鉴别。结果枳壳和桑白皮的薄层色谱鉴别方法专属性强。黄芩苷进样质量的线性范围为0．032～2．59tzg（r=0．9996），回收率为100．08％（RSD=1.60％）。结论建立的方法定性专属性强、定量准确度高，适用于宣肺清热合剂的质量控制。

Objective To establish quality standard of Xuanfeiqingre mixture. Methods TLC was used to qualitatively identify Fructus Aurantii and Cortex Mori in Xuanfeiqingre mixture, and HPLC method was used to quantitatively iden- tify baicalin in mixture. Results TLC identification for Fructus Aurantii and Cortex Mori was specific and distinct. Baicalin showed a good liner relationship within the range from 0.032 μg to 2.59 μg （r = 0.9996）, the average recovery was 100.08%, with RSD of 1.6%. Conclusion This established method is qualitatively exclusive and quantitatively ac- curate, which is suitable for quality control of Xuanfeiqingre mixture.