床旁即时凝血检测仪在抗凝治疗监测中的临床应用进展

Progress in clinical application of point-of-care testing device for antico-agulation monitoring

与检验科凝血检测仪检测国际标准化比值(INR)比较,POCT凝血检测仪的准确度较好,精密度良好。用床旁即时(POCT)凝血检测仪最主要的优势在于能缩短检测周转时间,同时提高患者的满意度。不仅提高了患者华法林抗凝治疗的质量,而且减少了血栓栓塞事件和降低了全因死亡率,不增加出血事件的风险。同时,可以明显提高患者用药的依从性及生活质量。美国等国家由药师管理的抗凝门诊中,POCT凝血检测仪的应用,方便医务人员及时调整华法林的用药剂量,保证患者用药安全。若能进一步提高POCT凝血检测仪检测INR的准确度,会更好地服务于临床。

Compared with laboratory INR, good accuracy and precision are observed with POCT device. The primary advantages of POCT device is rapid turn-around time, improving patients＇ satisfaction at the same time. Using POCT device not only improves the gouality of Warfarin anticoagulant therapy, but also reduces thromboembolic events and mortality, without increased risk for a serious bleeding event. With the INR measured by POCT device, patient＇s medi- cation compliance and life quality will be improved significantly. In anticoagulation clinics of the country such as America are managed by pharmacists, with the application of POCT device, medical workers can adjust the dosage of Warfarin conveniently and ensure patients＇ medication safety. If the accuracy of POCT device is improved, it will be better for INR control in patients who taking Warfarin.