双能X线在慢性肾脏病患者血管钙化中的应用

Application of dual-energy X-ray in vascular calcification in patients with chronic kidney disease

目的探讨双能X线骨密度检测在慢性肾脏病（CKD）患者血管钙化诊断中的应用价值。方法选取2013年1月~2014年12月本院接诊的42例CKD 3~5期患者作为研究对象,所有患者均行双能X线检查。以多层螺旋CT诊断为金标准,评价双能X线检测在CKD 3~5期患者血管钙化诊断中的敏感度和特异性。结果多层螺旋CT在CKD 3期、CKD 4期、CKD 5期的检出率分别为33.3%、52.2%、100.0%,双能X线的检出率分别为22.2%、43.5%、90.0%,且多层螺旋CT的总检出率为59.5%,与双能X线检测的50.0%比较,差异无统计学意义（P〉0.05）。以多层螺旋CT检测为金标准,双能X线检测的特异性为100.0%,敏感度为84.0%。结论双能X线可应用于检测CKD 3~5期患者的血管钙化,具有较好的临床价值。

Objective To exolore the application value of dual-energy X-ray in the detection of vascular calcification in chronic kidney disease（CKD） patients. Methods 42 cases of CKD 3-5 stages from January 2013 to December 2014 in our hospital were selected as the research objects.All patients were given dual-energy X-ray examination.The sensitivity and specificity of dual-energy X-ray examination in the diagnosis of vascular calcification in patients with CKD3-5 stages were evaluated by using the gold standard of the diagnosis of multi-slice spiral CT. Results The detection rate in CKD 3-5 stages by multi-slice spiral CT was 33.3%,52.2%,100.0% respectively,while the detection rate in CKD 3-5 stages by dual-energy X-ray was 22.2%,43.5%,90.0% respectively.The total detection rate of multi-slice spiral CT was 59.5%,the otal detection rate of multi-slice spiral CT was 50.0%,there was no significant difference（P0.05）.The specificity of dual energy X-ray detection was 84%,and the sensitivity was 100%,with the detection of multi slice spiral CT as gold standard. Conclusion Dual-energy X-ray can be used in the detection of vascular calcification in chronic kidney disease of 3-5 stages and indicates good clinical value.