糖脂双调方治疗2型糖尿病前期34例疗效观察

Effects of Tangzhi Shuangtiao Prescription on 34 Patients with Type 2 Pre-diabetes

目的:观察糖脂双调方治疗糖尿病前期的临床疗效。方法:选取糖尿病前期患者68例,随机分为治疗组和对照组各34例。两组患者均给予适当生活方式干预及健康教育,治疗组在此基础上加用自拟糖脂双调方治疗,6个月后观察两组患者干预前后空腹血糖(FBG)及餐后2 h血糖(PBG)、糖化血红蛋白(Hb A1c)、血脂(TG、TC、HDL-C、LDL-C)等。结果:两组患者治疗后FBG、2 h PG、Hb A1c均较治疗前下降(P<0.05或P<0.01);两组方法均能改善患者血脂代谢,治疗组TG降低明显,HDL-C升高,与治疗前比较,差异有统计学意义(P<0.05);治疗组疗效优于对照组,差异有统计学意义(P<0.05)。结论:糖脂双调方结合生活方式干预,能降低糖尿病前期患者血糖及血脂,预防糖尿病的发生。

Objective： To observe the clinical effects of Tangzhi Shuangtiao Prescription（TZSTP） in intervening patients with type 2 pre-diabetes. Method： The 68 patients with pre-diabetes were randomly divided into treatment group（34 cases） and con-trol group（34 cases）. All patients received lifestyle intervention and health education. Besides, patients in the treatment group were treated with self-made TASTP. After 6 months, the fasting blood glucose（FBG）, postprandial blood glucose（PBG）, glycosy-lated hemoglobin（Hb A1c）, blood lipids（TG, TC, HDL-C, and LDL-C）, and other indexes of the two groups were observed. Re-sults： After treatment, the content of FBG, 2 h PG and Hb A1 c decreased in both group（P0.05, P0.01）. Both methods of the two groups could improve the metabolism of blood lipids, TG of the treatment group decreased significantly and HDL-C in-creased（P0.05）. The Effects of the treatment group was better than that of the control group（P0.05）. Conclusions： TZSTP combined with lifestyle intervention could lower the blood glucose and blood lipids of type 2 pre-diabetes patients, thus preventing the occurrence of type 2 diabetes.