九里香化学成分和药理作用的研究进展

Research progress on chemical constituents and biological activities of Murraya exotica

九里香为芸香科九里香属植物,广泛分布于我国的南部以及亚洲一些热带和亚热带地区。目前,从中分离得到的化学成分主要有香豆素类、黄酮类、生物碱类以及挥发油等。现代药理研究表明,九里香具有杀虫、消炎镇痛、抗菌及抗氧化等作用。综述了九里香化学成分和药理作用的研究进展,为其药效物质基础、作用机制研究及开发利用提供理论依据。

Murraya exotica, a kind of plant in genus Murraya Koenig ex L. of Rutaceae family, is widely distributed in southern China and some tropical and subtropical regions of Asia. At present, the bioactive chemical constituents from this plant are mainly composed of coumarins, flavonoids, alkaloids, volatile oil, etc. Modern pharmacological researches show that M. exotica has insecticidal, anti-inflammatory analgesic, antibacterial, antioxidant effects, etc. The research progress on chemical constituents ofM. exoticaand their pharmacological activities are reviewed in this paper, which could provide a theoretical basis for the material basis of efficacy, mechanism of action and exploitation.