职业性黑变病并发氯痤疮8例临床分析

Clinical analysis of 8 cases of occupational melanosis complicated by occupational chloracne

目的:探讨职业性黑变病及职业性氯痤疮的诊断、治疗及预后。方法:对8例临床确诊的职业性黑变病并发职业性氯痤疮的临床资料进行分析并文献学习。结果:8例患者发病前均有明确的职业接触史,结合典型临床表现,以及脱离职业环境后皮损改变,诊断职业性黑变病并发氯痤疮明确。结论:对于从事接触石油、焦油类化学物及卤代芳烃化合物的工人,就业前应作皮肤科检查,加强个人防护,定期体检,以预防疾病的发生。

Objective： To discuss the diagnosis, treatment and prognosis of occupational melanosis with chloracne. Methods： The clinical data from eight patients with occupational melanosis and chloraene were analyzed, and literature was reviewed. Results： All eight patients had a history of occupational exposure before the lesions appeared. Based on their typical clinical manifestations and clearance of lesions after leaving the specific environment, the diagnosis of occupational melanosis complicated by chloracne was made. Conclusion： The results indicate that workers who are exposed to oil, tar and halogenated aromatic hydrocarbons should take dermatology examinations prior to taking the job. Regular medical examinations could effectively prevent the development of disease.