替罗非班治疗老年冠心病的临床研究

Clinical Research of tirofiban in the Treatment of Senile Coronary Heart Disease

目的：探讨替罗非班治疗老年冠心病的疗效. 方法：自2012年2月～2014年8月,我院应用替罗非班治疗老年冠心病患者98例,按照完全随机法将患者随机分为2组,即实验组和对照组,每组49例,2组患者均在一般治疗的基础上,实验组应用替罗非班治疗,对照组应用阿司匹林和氯吡格雷治疗. 治疗结束后观察2 组患者的疗效以及不良反应. 结果：实验组痊愈36例,有效12例,总有效率97. 96%,对照组痊愈31例,有效11例,总有效率85. 71%,2组相比差异明显（p〈0. 05）. 结论：替罗非班治疗老年冠心病有效,安全.

Objective：To investigate the curative effect of tirofiban in treatment of senile coronary heart disease. Methods：from 2012 February to 2014 August in our hospital, the application of tirofiban in the treatment of 98 cases of elderly patients with coronary heart dis-ease, according to completely randomized patients were randomly divided into two groups, namely experimental group and control group, 49 cases in each group, the two groups of patients on the basis of routine treatment, the experimental group application of tirofiban treat-ment, the control group use of aspirin and clopidogrel therapy. Observation of the curative effect and adverse reaction of two groups of pa-tients after treatment. Results：the experimental group 36 cases were cured, effective in 12 cases, the total efficiency of 97. 96%, control group 31 cases were cured, effective in 11 cases, the total efficiency of 85. 71%, difference between the two groups was significantly （p〈0. 05）. Conclusion：the treatment of tirofiban in elderly patients with coronary heart disease effectively, safety.