摘要
OBJECTIVE:To review and discuss the Chinese and English literature on the use of pain-related evoked potentials(PREP) and short-latency somatosensory EP(SLSEP) in acupuncture research.METHODS:China National Knowledge Infrastructure Database and MEDLINE were searched for the following key words:acupuncture and PREP or SLSEP.RESULTS:Thirty-seven articles were included in the review.Researchers usually use PREPs to study the analgesic effect of acupuncture,observe influential factors,or for mechanistic exploration.In the SLSEP studies,researchers focused on response characteristics of acupuncture,acupoint specificity,and influential factors of the treatment.There were some problems with the study design and conclusions.CONCLUSION:Researchers could use PREP and SLSEP to objectively validate the effects of acupuncture and explore its mechanisms using nerve electrophysiology.Further studies can benefit from observing more acupoints' effects using PREPs or SLSEPs and investigating the placebo effect of acupuncture.
OBJECTIVE：To review and discuss the Chinese and English literature on the use of pain-related evoked potentials（PREP） and short-latency somatosensory EP（SLSEP） in acupuncture research.METHODS：China National Knowledge Infrastructure Database and MEDLINE were searched for the following key words：acupuncture and PREP or SLSEP.RESULTS：Thirty-seven articles were included in the review.Researchers usually use PREPs to study the analgesic effect of acupuncture,observe influential factors,or for mechanistic exploration.In the SLSEP studies,researchers focused on response characteristics of acupuncture,acupoint specificity,and influential factors of the treatment.There were some problems with the study design and conclusions.CONCLUSION：Researchers could use PREP and SLSEP to objectively validate the effects of acupuncture and explore its mechanisms using nerve electrophysiology.Further studies can benefit from observing more acupoints＇ effects using PREPs or SLSEPs and investigating the placebo effect of acupuncture.
基金
Supported by the National Basic Research Program of China(973 Program)-the Effect of De Qi on Acupoint Specific Effect Based on Meridians and its Characteristics and Molecular Response Mechanisms(No.2012CB518506)
Research on Acupoint Specificity in Regulating Uterus(No.2006CB504503)
Research on Laws of Acupoint Effects(No.2005CB523308)
National Natural Science Foundation of China-Traditional Acupuncture Formula for Inducing Labor(Hegu-Sanyinjiao,LI4-SP6)Electro-acupuncture Parameter Optimization and Molecular Response Mechanisms(No.30973793)
the Doctoral Program of Higher Education of Ministry Education of China-Research Based on Primary Dysmenorrhea on Electric Characteristics of Acupoints Which Were Different Ones on the Same Meridians or Similar Ones on the Different Meridians(No.20090013110005)
