依据证候要素辨证组方治疗慢性心力衰竭的疗效观察

Observation of the Clinical Efficacy on Chronic Heart Failure on Basis of Syndrome Essence Differentiation

目的:评价基于证候要素辨证论治慢性心力衰竭的疗效及对超声LVEF值、6 min步行试验(6MWT)、患者生活质量的改善。方法:将55例慢性心衰患者随机分为试验组和对照组,对照组给予常规西药治疗,试验组在西药常规治疗基础上通过证候要素辨证给予相应的中药治疗。观察患者治疗前后的中医证候疗效、超声LVEF值、6 min步行试验结果、慢性心衰生存质量量表总积分的变化。结果:试验组的有效率为66.67%,对照组为72%,差异无统计学意义(P>0.05);2组超声LVEF值、6 min步行试验、慢性心衰生存质量量表总积分较治疗前均有提高,差异有统计学意义(P<0.05),组间比较无统计学差异(P>0.05)。结论:以证候要素辨证论治慢性心衰可以改善中医症状,提高LVEF值及慢性心衰患者的生存质量,值得进一步研究。

Objective：To observe the clinical efficacy of syndrome essence differentiation based treatment in chronic heart failure（CHF） and the improvement in LVEF value,6MWT and life quality of patients.Methods：Patients with chronic heart failure of 55 cases were randomly divided into two groups：treatment group and control group,both groups were given conventional western medicine treatment while the treatment group were also given Chinese medicine treatment based on Chinese medicine syndrome essence differentiation.Then the Chinese medicine symptom（TCM）,LVEF,6MWT and quality of life were observed.Results：Clinical total effective rate of the two groups were not significant different,for treatment group,it was 66.67%and control group 72%（P0.05）.LVEF,6MWT and the quality of life were promoted in each group with significant differences（P 0.05）,but without statistic significances between two groups（P 0.05）.Conclusion：It needs further study to figure out the treatment based on syndrome differentiation in improving Chinese medicine symptoms,LVEF and the quality of life.