阿托品联合奥美拉唑治疗急性胃炎100例临床疗效观察

Clinical efficacy of atropine combined with omeprazole in the treatment of 100 patients with acute gastritis

目的探讨阿托品联合奥美拉唑治疗急性胃炎的临床疗效。方法以该院收治的100例急性胃炎患者为研究对象,根据临床治疗方式的不同分为对照组与观察组,每组50例。对照组采用山莨菪碱联合奥美拉唑治疗,观察组采用阿托品联合奥美拉唑治疗。两组均治疗2周。在治疗结束后对比两组患者的临床疗效。结果观察组显效38例,有效11例,无效1例。对照组显效28例,有效15例,无效7例。观察组疗效优于对照组(Z=4.84,P<0.05);观察组不良反应发生率为8.0%,明显低于对照组的24.0%(P<0.05)。观察组首次用药后显效率为76.0%,高于对照组的44.0%(P<0.05)。结论阿托品联合奥美拉唑治疗急性胃炎的临床疗效显著,能够快速缓解急性胃炎患者的疼痛症状,且治疗安全性高,不良反应少。

Objective To investigate the clinical efficacy of atropine combined with omeprazole in the treatment of patients with acute gastritis. Methods One hundred patients with acute gastritis were divided into the control group( n = 50) and the observation group( n = 50). The control group was treated with anisodamine combined with omeprazole,and the observation group was treated with atropine combined with omeprazole. The clinical efficacy was compared between the two groups. Results The effective rate of the observation group was significantly higher than that of the control group( P < 0. 05). The incidence of adverse reactions was obviously lower in the observation group than that in the control group( P < 0. 05). The rate of significant efficiency for the first time after the medication in the observation group( 76. 0%) was significantly higher than that in the control group( 44. 0%)( P < 0. 05). Conclusion Atropine combined with omeprazole is safe and effective in the treatment of acute gastritis,which quickly reduces the symptom of pain and improves the patients' quality of life.