四君子汤治疗脾虚证实验研究进展

Experimental Research Progress of Four Gentlemen Decoction in Treating Spleen Deficiency Syndrome

脾虚证为目前临床常见证型之一,机体长时间的脾虚会引发很多疾病如功能性消化不良、慢性腹泻、慢性胃炎、消化性溃疡等。因此越来越多的人们开始从各个方面探究脾虚证的发病机制。而四君子汤又是治疗脾虚证的经典方剂。四君子汤的作用是补气健脾,具有增强机体免疫、保护胃黏膜、调节胃肠运动、调节神经内分泌、调节胃肠激素、抗菌消炎、提高能量代谢以及促进细胞增殖等的作用。以上这些药理作用与四君子汤在临床治疗脾虚症候的疾病有着密切关系。因此对近十年四君子汤治疗脾虚证的实验研究作一综述。为临床上治疗关于脾虚证而出现的一些疾病提供了科学的实验依据。

Spleen deficiency syndrome is one of the common clinical syndromes,spleen deficiency in the body for a long time will lead to many diseases,such as functional digestive adverse,chronic diarrhea,chronic gastritis,peptic ulcer,etc.Therefore,more and more people begin to explore the pathogenesis of spleen deficiency syndrome from various aspects. The Four Gentlemen decoction is the classic prescription for the treatment of spleen deficiency syndrome. The effect of Four Gentlemen decoction is invigorating qi and strengthening the spleen,enhance immunity,protect the gastric mucosa,regulation of gastrointestinal motility and neuroendocrine regulation,regulation of gastrointestinal hormone,anti-inflammatory antibacterial,improve the energy metabolism and promote cell proliferation. These diseases,pharmacological action and clinical treatment of spleen in Four Gentlemen decoction syndrome has a close relationship. The experimental study of nearly ten years of Four Gentlemen decoction on spleen deficiency syndrome were reviewed. Provide a scientific experimental basis for the treatment of some diseases of spleen deficiency and clinical.