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尿酸与慢性肾脏病关系的研究进展

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摘要 高尿酸血症在高血压、代谢综合征、肾脏疾病患者中是非常常见的。然而,高尿酸血症与慢性肾脏病(CKD)之间的关系仍没有定论。近几十年来,主流观点认为高尿酸血症是肾功能不全的结果,被认为是肾脏损害的标志因子,而不是肾病发生发展的原因。然而,最近的流行病学研究显示高尿酸血症与高血压、慢性肾病、心血管事件和死亡的风险增加是独立相关的,而且临床及动物实验也支持这一说法。
作者 张丽英
出处 《器官移植内科学杂志》 2015年第1期17-24,共8页 Journal of Transplant Medicine
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