腰椎内固定术后椎间盘T2-mapping成像的可行性和可重复性

MR T2-mapping of Intervertebral Disk after Internal Fixation Surgery of Lumbar Spine:A Feasibility and Reproducibility Study

目的探讨腰椎内固定术后T2-mapping成像定量评估邻近节段椎间盘退变的可行性和可重复性。方法 24例患者于腰椎内固定术前1周内及术后6-8周分别行腰椎MR T2-mapping成像检查,并测量邻近节段椎间盘髓核的T2值。比较同一观察者不同时间和不同观察者之间测量结果的可重复性。结果 24例患者均成功测量邻近节段椎间盘髓核的T2值。内固定近侧邻近椎间盘髓核术前和术后的T2值分别为93.2±22.3ms和95.5±20.1ms,差异无统计学意义(t=-1.00,P>0.05)。远侧邻近椎间盘髓核术前和术后的T2值分别为87.9±27.7ms和83.7±23.0ms,差异无统计学意义(t=1.77,P>0.05)。同一观察者或不同观察者间的组内相关系数(ICC)为0.85-0.94(P<0.01)。结论腰椎内固定术后T2-mapping成像测量T2值是可行的,且可重复性高,有助于定量评估邻近节段椎间盘的退变情况。

Objective To explore the feasibility and reproducibility of MR T2-mapping technique in evaluating intervertebral disk degeneration of adjacent segment after internal fixation surgery. Methods Within 1 week preoperatively and 6 to 8 weeks postoperatively,24 patients were underwent T2-mapping examination. The T2 value of nucleus pulposus was measured by two senior MRI radiologists. To assess the reproducibility of this evaluation, inter-and intra-observer statistics were performed. Results The T2 values of 24 patients were measured successfully. The preand postoperative T2 values of the adjacent proximate disks were 93.2±22.3ms and 95.5±20.1ms respectively（t=-1.00,P0.05）,and the pre- and postoperative T2 values of the adjacent distal disks were 87.9±27.7ms and 83.7±23.0ms（t=1.77,P0.05）.The inter- and intra-observer analysis yielded intraclass correlation coefficients（ICC） for measures in a range from 0.85 to 0.94（P0.01）. Conclusion MR T2-mapping examination after internal fixation surgery is feasible, it will be a potential quantitative method in evaluating intervertebral disk degeneration of adjacent segment for its excellent reproducibility.