摘要
目的:观察电针配合偏振光对腰椎间盘突出症患者腰腿疼痛的镇痛效果,以及对血清基质金属蛋白酶-3(MMP-3)含量的影响。方法:将93例腰椎间盘突出症患者,分为电针配合偏振光组(观察组)31例、电针组(对照1组)30例和偏振光组(对照2组)32例。观察组取肾俞、大肠俞、环跳、委中、承山、昆仑穴,行电针治疗,并配合偏振光照射;对照1组行电针治疗,取穴同观察组;对照2组行偏振光照射治疗。观察3组治疗前后疼痛视觉模拟评分(VAS)及血清基质金属蛋白酶(MMP-3)含量变化情况。结果:治疗15d后,3组VAS及血清MMP-3含量均较治疗前明显降低(P<0.05),且观察组更低于对照1组及对照2组(P<0.05),对照1组与对照2组间比较差异无统计学意义。结论:电针配合偏振光为治疗腰椎间盘突出症较理想的方法,其机制可能与治疗后病变部位血清MMP-3的降低有关。
Objective: To observe the clinical effectiveness of electroacupuncture combined with polarized light for lumbar disc lesions and analyze its effect on serum matrix metalloproteinase-3 (MMP-3) in patients with lumbar disc lesions. Method: Ninety-three cases of lumbar disc lesions were randomly divided into three groups: the eleetroaeu- puncture combined with polarized light group (n= 31) (treatment group), the electroacupuncture group (n= 30) (control group 1), and polarized light group (n=32) (control group 2). The treatment group was given electroacu- puncture on Shenshu (BL 23), Dachangshu (BL 25), Huantiao (GB 30), Weizhong (BL 40), Chengshan (BL 57), and Kunlun (BL 60) and polarized light, once a day for 15 days. The control groups were treated as the treatment group with the electroacupuncture and polarized light respectively. After treatment the visual analogue scale (VAS) and the MMP-3 contents in serum were observed. Result: After treatment for 15 days, the VAS values and serum MMP-3 levels were significantly decreased in the three groups as compared with those before treatment (P〈0. 05). The VAS values and serum MMP-3 levels in treatment group were obviously decreased as compared with the control groups (P〈0.05), and there was no significant difference between the two control groups. Conclusion: Electroacu- puncture combined with polarized light has a good effectivness on lumbar disc lesions pain probably by decreasing the serum MMP-3 levels in the local site.
出处
《中国康复》
2015年第5期358-360,共3页
Chinese Journal of Rehabilitation
基金
国家自然科学基金青年项目(No.81403485)