摘要
目的:观察电针配合偏振光对腰椎间盘突出症患者腰腿疼痛的镇痛效果,以及对血清基质金属蛋白酶-3(MMP-3)含量的影响。方法:将93例腰椎间盘突出症患者,分为电针配合偏振光组(观察组)31例、电针组(对照1组)30例和偏振光组(对照2组)32例。观察组取肾俞、大肠俞、环跳、委中、承山、昆仑穴,行电针治疗,并配合偏振光照射;对照1组行电针治疗,取穴同观察组;对照2组行偏振光照射治疗。观察3组治疗前后疼痛视觉模拟评分(VAS)及血清基质金属蛋白酶(MMP-3)含量变化情况。结果:治疗15d后,3组VAS及血清MMP-3含量均较治疗前明显降低(P<0.05),且观察组更低于对照1组及对照2组(P<0.05),对照1组与对照2组间比较差异无统计学意义。结论:电针配合偏振光为治疗腰椎间盘突出症较理想的方法,其机制可能与治疗后病变部位血清MMP-3的降低有关。
Objective： To observe the clinical effectiveness of electroacupuncture combined with polarized light for lumbar disc lesions and analyze its effect on serum matrix metalloproteinase-3 （MMP-3） in patients with lumbar disc lesions. Method： Ninety-three cases of lumbar disc lesions were randomly divided into three groups： the eleetroaeu- puncture combined with polarized light group （n= 31） （treatment group）, the electroacupuncture group （n= 30） （control group 1）, and polarized light group （n=32） （control group 2）. The treatment group was given electroacu- puncture on Shenshu （BL 23）, Dachangshu （BL 25）, Huantiao （GB 30）, Weizhong （BL 40）, Chengshan （BL 57）, and Kunlun （BL 60） and polarized light, once a day for 15 days. The control groups were treated as the treatment group with the electroacupuncture and polarized light respectively. After treatment the visual analogue scale （VAS） and the MMP-3 contents in serum were observed. Result： After treatment for 15 days, the VAS values and serum MMP-3 levels were significantly decreased in the three groups as compared with those before treatment （P〈0. 05）. The VAS values and serum MMP-3 levels in treatment group were obviously decreased as compared with the control groups （P〈0.05）, and there was no significant difference between the two control groups. Conclusion： Electroacu- puncture combined with polarized light has a good effectivness on lumbar disc lesions pain probably by decreasing the serum MMP-3 levels in the local site.
出处
《中国康复》
2015年第5期358-360,共3页
Chinese Journal of Rehabilitation
基金
国家自然科学基金青年项目(No.81403485)
