银杏叶胶囊对冠心病PCI术后再狭窄及左室收缩功能的影响

Effect of Yinxingye Capsules on Left Ventricular Systolic Function and Restenosis in Patients with Coronary Artery Disease after PCI

目的观察银杏叶胶囊对经皮冠状动脉介入治疗(PCI)患者术后再狭窄以及左室收缩功能的影响。方法80例冠心病PCI术后患者随机分为两组。对照组仅给予常规西药治疗,治疗组在对照组治疗的基础上加用银杏叶胶囊。治疗12个月后比较两组患者治疗前后的心电图、超声心动图、冠脉造影(CAG)等检查结果以及临床疗效。结果治疗组临床疗效、心电图疗效及冠脉造影再狭窄率与对照组相比较,差异均具有统计学意义(P<0.05);同时,治疗组左室射血分数(LVEF)、每搏输出量(SV)、每分输出量(CO)值均明显改善,与对照组相比较差异具有统计学意义(P<0.05)。结论银杏叶胶囊能有效降低冠心病患者PCI术后再狭窄发生率,同时能有效改善其左室收缩功能,提高心输出量。

Objective To observe the effect of Yinxingye capsules to prevent the restenosis after pereutaneous coronary intervention（ PCI） in patients with coronary artery disease（ CAD）. Methods 80 cases of CAD after PCI were randomly divided into two groups. The control group was only given conventional western medicine treatment,the treatment group added with Yinxingye capsules based on the control group. To compare the changes of the ECG,ultrasonic cardiogram（ UCG）,coronary angiography（ CAG） and clinical efficacy between two group. Results After treatment,the ECG,UCG,CAG results and clinical efficacy of patients in treatment group were significantly improved,compared with the control group,the differences were significant（ P〈0. 05）. At the same time,the level of LVEF,SV and CO of patients in treatment group were significantly improved,compared with the control group,the difference was significant（ P〈0. 05）. Conclusions Yinxingye capsules in patients with coronary heart disease can reduce the incidence of restenosis after PCI,and effectively improve the left ventricular systolic function and cardiac output.