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宫颈癌术后阴道断端复发调强放射治疗联合插植调强近距离后装治疗疗效观察

Impact of Intensity Modulated Radiotherapy Concurrent With Implanted Intensity Modulated Brachytherapy for Vaginal Stump Recurrence of Cervical Cancer After Surgery
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摘要 目的分析宫颈癌术后阴道断端复发调强放射治疗联合插植调强近距离后装治疗近期疗效。方法 2012年1月~2014年12月本院收治的30例宫颈癌术后阴道断端复发患者,均行放射治疗,24例联合全身化疗。放射治疗采用调强放射治疗联合插植调强近距离后装治疗。化疗方案为紫杉醇+卡铂、顺铂+5-FU。结果随访时间为6~45个月,中位随访时间27个月,随访率100%。完全有效率CR及部分有效率PR分别为80.00%(24/30)、93.33%(28/30)。4例出现I^II度放射性直肠炎。结论宫颈癌术后阴道断端复发调强放射治疗联合插植调强近距离后装治疗疗效满意,副反应小,患者能耐受。 Objective To observe the efficacy and toxicities of intensity modulated radiotherapy concurrent with implanted intensity modulated brachytherapy for vaginal stump recurrence of cervical cancer after surgery. Methods From January 2012 to December 2014,30 patients with vaginal stump recurrence of cervical cancer after surgery were treated by intensity modulated radiotherapy concurrent with implanted intensity modulated brachytherapy. Results The overall response rate was 93.33%. No patient suffered more than grade III toxicities. Concusion Intensity modulated radiotherapy concurrent with implanted intensity modulated brachytherapy is effective for recurrent vaginal stump of cervical cancer after surgery. Bracytherapy as post-radiation boost dilived more conformal doses to the targets. The adverse reaction was tolerable.
出处 《中国卫生标准管理》 2015年第27期59-61,共3页 China Health Standard Management
关键词 宫颈癌 手术治疗 阴道断端 复发 放射治疗 调强放射治疗 近距离后装治疗 化学治疗 Cervical cancer Operation Vaginal stump Recurrence Radiotherapy Intensity modulated radiotherapy Brachytherapy Chemotherapy
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参考文献10

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