甲状旁腺切除对继发性甲状旁腺功能亢进的维持性血透患者左心功能及生存质量的影响

Effects of parathyroidectomy on left ventricular function and quality of life in uremic patients with secondary hyperparathyroidism

目的:观察甲状旁腺切除术对继发性甲状旁腺功能亢进的维持性血透患者的左心功能及生存质量的影响。方法:以接受甲状旁腺切除术的继发性甲状旁腺功能亢进的维持性血透患者45例为手术组,以同期在血液透析中心进行透析的无甲状旁腺功能亢进的维持性血透患者45例为对照组。观察手术组患者在接受甲状旁腺切除术前后的左心功能,评价其生存质量,与对照组进行比较。结果:手术组患者在接受手术前,SF-36各项评分均明显低于对照组,左心功能比对照组差。手术后6个月,SF-36各项评分及左心功能明显好于手术前,与对照组无明显区别。结论:甲状旁腺切除术能改善患者的左心功能,提高患者的生存质量。

Objective：To observe the effect of parathyroidectomy for hemodialysis patients with secondary hyperparathyroidism in left heart function and quality of life.Method：Forty-five secondary hyperparathy roidism patients with maintenance hemodialysis who undertook parathyroid resection were included into operation group,other 45 hemodialysis cases without hyperparathyroidism during the same period were included into control group.The left heart function before and after parathyroidectomy and the quality of life were evaluated and compared between the two groups.Result：In preoperation,the SF-36 scores in operation group were significantly lower than those in control group,and the left ventricular function was worser than control group.Six months after operation,the SF-36 score and left ventricular function were significantly better than preoperation in operation group,and had no significant difference compared with control group.Conclusion：Parathyroidectomy can improve the left ventricular function conclusion,and improve the quality of life.