酚妥拉明治疗小儿急性肾小球肾炎高血压疗效分析

Effect of phentolamine on hypertension in children with acute glomerulonephritis

目的：探讨酚妥拉明治疗小儿急性肾小球肾炎高血压的临床疗效。方法随机选取嵩县人民医院2011年7月至2013年11月收治的确诊为急性肾小球肾炎高血压患儿90例，将其随机平均分配为实验组和对照组，其中对照组患者采用利血平进行治疗，实验组患儿在对照组的治疗基础上加用酚妥拉明进行治疗，对比两组患儿的临床治疗效果。结果实验组患儿的临床治疗效果及临床症状改善时间均明显优于对照组患儿，差异有统计学意义（ P＜0．05）。结论采用酚妥拉明治疗小儿急性肾小球肾炎高血压，能够有效促进患儿血压的快速平复，疗效显著，安全可靠，建议在临床上进一步推广。

Objective To investigate the clinical efficacy of phentolamine on hypertension in children with acute glomerulonephritis.Methods From July 2011 and November 2013, ninety cases of acute glomerulonephritis children with high blood pressure were chosen, and were randomly divided into the experiment group and the control group.The patients in control group were treated with reserpine treatment, and the patients in the experiment group were given phentolamine in addition, the clinical out-comes of the two groups were compared.Results The clinical results and clinical symptoms improve-ment time in children of the experiment group were significantly better than those in the control group, the differences were significant（ P〈0.05） .Conclusions Phentolamine for the treatment of hypertension in children with acute glomerulonephritis can effectively promote the rapid recovery of blood pressure, is safe and reliable, so it is recommended to be further promoted in clinical practice.