儿童急性白血病中枢神经系统颅脑浸润CT与MRI表现

CT and MRI Manifestations of Craniocerebral Invasion in Children with Acute Leukemia

目的探讨儿童急性白血病颅脑浸润的CT及MRI表现。方法回顾性分析经病理证实的18例白血病患儿颅脑CT与MRI表现,所有病例均未行化疗及颅内放疗。结果 18例白血病患儿异常影像学表现包括:颅骨浸润12例,柔脑膜浸润1例,硬脑膜受累3例,其中2例累及邻近骨质及软组织,颅内血管病变2例。结论儿童急性白血病颅脑浸润的影像学表现多样,MRI多序列扫描及增强扫描可较好地显示儿童白血病中枢神经系统病变,有助于诊断和鉴别诊断。

Objective To document the CT and MRI findings of brain in children with acute leukemia. Methods CT scans and MR images were reviewed retrospectively in 18 childhood leukemia. All cases were not received chemotherapy and intracranial radiation. Results The imaging abnormalities seen in 18 patients during acute leukemia included skull leukemic infiltration（ n = 12,meningeal leukemia（ n = 1）,dura matter infiltration（ n = 3） with bone and soft tissue involvement in 2 cases,cerebrovascular disorders（ n = 2）. Conclusion The imaging manifestations of childhood leukemia are diverse,MRI with multiple sequence scans and contrast enhancement can well display the lesion of central nervous system leukemia in children.