芪甲酸类化合物的合成及其对HL-60细胞增殖的影响

SYNTHESIS OF STILBENE-4-CARBOXYLIC ACID DERIVATIVES AND ITS EFFECTS ON THE PROLIFERATION OF HL-60 CELL IN CULTURE

本文报道十二个芪甲酸类化合物(十个未见文献报道)的合成及其对HL-60细胞增殖的影响初步的结果,其中有五个化合物(Ⅱ_b 、Ⅱ_d、Ⅱ_t、Ⅱ_h、Ⅱ_k)在不同浓度时具有杀死HL-60细胞的作用。

In this paper, twelvestilbene-4-Carboxylic acid derivatives (10were new compounds) were synthesizedand evaluated the effects on the prolifera-tion of HL-60 cell in the culture Therewere 5 compounds (Ⅱb, Ⅱd, Ⅱf, Ⅱh, Ⅱk)possessed the effects of killing HL-60 cellat differente concentration.