中医药治疗肿瘤放疗、化疗后腹泻的疗效评价方法评述

Comment on Efficacy Evaluation Methods of Chinese Medicine in Treating Diarrhea of Tumor Patients after Radiotherapy and Chemotherapy

对现有中医药治疗放疗、化疗后腹泻疗效评价方法进行汇总,认为目前最常用的疗效评价方法主要有治愈率、有效率等率的计算与比较,采用现代医学标准进行病情程度的评价,中医症状评分,根据现代医学症状、体征及相应实验室与影像学检查结果评价等方法。目前疗效评价方法存在的主要问题:以治愈率、有效率等率的结果代替原始数据,影响研究真实性与科学性;无法体现中医治疗特色与优势;存在片面性及缺乏针对性;忽视安全性的评价。通过分析认为,结合现代医学实验室检查及影像学分析、配合患者生存质量评价、重视安全性评价是中医药治疗肿瘤放疗及化疗后腹泻较为全面的评价方法。

The researchers summarized the existing evaluation methods of therapeutic efficiency about TCM treating diarrhea after radiotherapy and chemotherapy. They thought that the most frequently-used evaluation methods of therapeutic efficiency at present are mainly calculation and comparison about kinds of rates,such as cure rate,effective rate. Current practice uses the standard of western medicine to evaluate illness degree,symptom scores of TCM,evaluation according to the symptoms,signs and corresponding results from laboratory and imageological examination and so on. At present,evaluation methods of therapeutic efficiency have the following problems： using rates such as cure rate and effective rate instead of the original data influences authenticity and scientificity of research;unable to reflect features and advantages of TCM treatment; existing one-sidedness and lacking of pertinence; as well as ignoring the evaluation of security. The researchers thought that combining with modern medical laboratory tests and imaging analysis,cooperating with evaluation of patients＇ survival quality and attaching great importance to the evaluation of security are more comprehensive evaluation method of Chinese medicine in treating diarrhea after radiotherapy and chemotherapy.