犬尿喹啉酸与精神分裂症
摘要
犬尿喹啉酸(kynurenic acid,KYNA)是N-甲基-D-天门冬氨酸受体(NMDAR)的竞争性拮抗剂和a7烟碱乙酰胆碱受体(a7n AChR)的非竞争性拮抗剂,脑中KYNA浓度的变化在精神分裂症病理生理中发挥着重要的作用。
出处
《国际精神病学杂志》
2015年第5期43-46,共4页
Journal Of International Psychiatry
基金
国家科技部十二.五科技计划支撑课题(2012BAI01B05)
国家自然科学青年基金项目(81201058)
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