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犬尿喹啉酸与精神分裂症

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摘要 犬尿喹啉酸(kynurenic acid,KYNA)是N-甲基-D-天门冬氨酸受体(NMDAR)的竞争性拮抗剂和a7烟碱乙酰胆碱受体(a7n AChR)的非竞争性拮抗剂,脑中KYNA浓度的变化在精神分裂症病理生理中发挥着重要的作用。
作者 韩娇 陈浩 陈振华 王高华 苏俊杰
机构地区 武汉大学人民医院精神科 湖北省京山县精神卫生中心 湖北省荆门第二医院精神科
出处 《国际精神病学杂志》 2015年第5期43-46,共4页 Journal Of International Psychiatry
基金 国家科技部十二.五科技计划支撑课题(2012BAI01B05) 国家自然科学青年基金项目(81201058)
关键词 犬尿喹啉酸 精神分裂症 犬尿酸途径
分类号 R749.3 [医药卫生—神经病学与精神病学]
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参考文献20

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二级参考文献29

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国际精神病学杂志
2015年 第5期

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