摘要
1型糖尿病与自身免疫性多腺体综合征是自身免疫性疾病,二者存在相关性,自身免疫性疾病是在遗传易感基因的基础上,外界环境等因素的诱发引起机体细胞免疫和体液免疫失衡,受影响的器官出现炎性细胞浸润,机体产生针对靶器官相应的自身抗体,最终导致受累器官功能破坏,表现出相应临床症状。
Type 1 diabetes mellitus and autoimmune polyglandular syndrome diseases are autoimmune disea-ses. There is a close correlation between them. The autoimmune pathogenesis is the genetic basis of susceptibility to en-vironmental factor and other factors,resulting in immune imbalance between cellular and humoral immunity. There are inflammatory cells infiltration in affected organs and antibodies against target organs. Eventually,affected organs have dysfunction and show corresponding symptoms.
出处
《中华实用儿科临床杂志》
CAS
CSCD
北大核心
2015年第20期1531-1533,共3页
Chinese Journal of Applied Clinical Pediatrics