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轴后多指(趾)的基因调控研究新进展 被引量:2

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摘要 轴后多指(趾)是常见的先天畸形。肢端发育通过复杂的细胞间通讯和基因表达网络来调控,其中任何一个基因的突变将可能导致不同类型多指(趾)或其他肢端发育异常。综合征型轴后多指(趾)的基因调控主要与Shh-Gli3通路的基因有关。通过家系分析发现5个非综合征型轴后多指(趾)基因座,仅有一个家系的Gli3基因被确定与发病有关。
出处 《山东医药》 CAS 北大核心 2015年第38期91-93,共3页 Shandong Medical Journal
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参考文献39

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