D-二聚体与凝血因子检测对普外科手术患者术后深静脉栓塞发生的预防价值

The Prevention Value of D-dimer and Coagulation Factor Detection on Patients with Deep Vein Thrombosis after General Surgery

目的:探讨D-二聚体(D-Dimer,D-D)与凝血因子检测对普外科手术患者术后深静脉栓塞形成(deep vein thrombosis,DVT)的预防价值。方法:选取2014年1月-2015年1月本院收治的普外科手术患者48例作为研究对象,分为术后无深静脉栓塞32例(非DVT组),术后有深静脉栓塞16例(DVT组)。分别于术前及手术后第1、3、7天检测静脉血中D-D、纤维蛋白原(FIB)。结果:与术前相比,两组的术后第1、3天D-D、FIB水平明显增加,与术前比较差异均有统计学意义(P<0.05);术后第7天非DVT组D-D、FIB水平下降至术前水平,与术前比较差异均无统计学意义(P>0.05);而DVT组D-D、FIB水平则明显增加,与术前比较差异均有统计学意义(P<0.05)。结论:D-二聚体与FIB检测对普外科术后深静脉栓塞发生有较好的预防价值,值得临床推广。

Objective：To investigate the prevention value for patients with deep vein thrombosis after general surgery detected by D- dimer（D-Dimer,DD） and coagulation factor. Method：48 inpatients with general surgical from January 2014 to January 2015 in our hospital were selected and divided into without deep vein thrombosis group for 32 cases（non-DVT group）and deep vein thrombosis group for 16 cases（DVT group）.D-D and fibrinogen（FIB） in blood were detected respectively before surgery and after surgery of 1 day,3 and 7 days. Result：D-D and FIB levels of patients in two groups at first and third day after surgery were significantly increased, compared with before surgery the differences were statistically significant（P〈0.05）. D-D and FIB levels in the non-DVT group at the 7th day after surgery decreased to the preoperative level,compared with before surgery the differences were no statistically significant（P〉0.05）.The D-D and FIB levels at the 7th day after surgery in the DVT group were significantly increased,compared with the preoperation,the differences were statistically significant（P〈0.05）.Conclusion：Determination of D-dimer and coagulation factor have better preventive values for deep vein thrombosis after general surgery,it is worthy of clinical promotion.