可吸收止血微球在肝脏部分切除术中的应用

Application of absorbable hemostatic microspheres in liver resection

目的：观察可吸收止血微球在肝脏手术中的止血效果。方法将2013年6月～2014年12月在我院就诊的40例择期行肝脏部分切除术的患者随机分为两组，实验组应用可吸收止血微球进行肝脏断面止血，对照组采用传统的纱布填塞按压止血。比较术中止血情况、止血时间及术后12h、1d、2d、3d引流情况。结果实验组手术时间和止血时间分别为（210.5±27.3）、（3.11±0.97）min，对照组手术时间和止血时间分别为（235.6±30.35）、（5.45±1.56）min，两组比较差异有统计学意义（P〈0.05）。实验组术后12 h、1 d、2 d引流量为（47.32±12.57）、（89.52±23.97）、（45.43±13.11）ml，少于对照组的（55.97±15.21）、（119.67±23.11）、（57.67±14.10）ml，差异有统计学意义（P〈0.05）。结论可吸收止血微球在肝脏切除术中止血效果明显，能有效缩短止血时间，减少术后引流量。

Objective To observe the hematischesis effect of absorbable hemostatic microspheres in liver operation. Methods 40 patients with elective liver resection from June 2013 to December 2014 of our hospital were randomly di-vided into two groups.The experimental group were used absorbable hemostatic microspheres for liver section hematis-chesis,the control group were used traditional gauze pressure to stop the bleeding.The situation of hematischesis during operation,stopping bleeding,drainage situation after operation 12 h,1 d,2 d,3 d were compared. Results The operation time and stopping bleeding was respectively （210.5±27.3）min and （3.11±0.97）min in experimental group.The operation time and stopping bleeding was respectively （235.6±30.35）min and （5.45±1.56）min in control group,the difference was statistical significance（P〈0.05）.The drainage volume after operation 12 h,1 d,2 d was respectively（47.32±12.57）,（89.52±23.97）,（45.43±13.11）ml in experimental group,less than that respectively （55.97±15.21）,（119.67±23.11）,（57.67±14.10）ml in control group,and the difference was statistical significance （P〈0.05）. Conclusion The hematischesis effect of ab-sorbable hemostatic microspheres in liver operation is obvious.It can effectively shorten the bleeding time and reduce postoperative drainage volume.