手术治疗阴囊Paget's病13例临床分析

Clinical analysis of 13 cases of scrotal Paget' s disease treated by surgery

目的：探讨阴囊Paget＇s病的临床病理特征。方法：回顾性分析本院2005年4月一2014年5月收治的13例病理确诊为阴囊Paget＇s病患者的临床病理及预后资料。结果：13例患者中，4例为术后复发患者；10例进行广泛切除，3例进行广泛切除＋淋巴结清扫术，术后1例发生伤口感染；术后共随访6～106个月，4例复发患者中1例术后未再复发，另3例术后再次复发，其中1例因其他疾病死亡，9例首诊患者均未复发。结论：病灶广泛切除是治疗阴囊Paget＇s病的首选治疗手段，复发后再次手术仍能获得较好疗效。

Objective：To investigate the clinicopathological features of scrotal Pagetg disease. Methods：Analyzed retrospectively the clinical pathological and prognosis data of 13 cases of scrotal Paget＇s disease. Results： All cases contained 4 cases which were postoperative recurrence patients and 9 cases were first visit confirmed by biopsy and treated by surgery. The selection of operation covered wide excision （10 cases ） and wide excision add lymphadenecto- my （ 3 cases）. 9 patients with first visit were not all recrudesced, while 3 patients of postoperative recurrence were re- lapsed again and only one dead. All patients were followed up for 6 - 106 months. Conclusion：The wide excision is the first choice of treatment of scrotal Paget~ disease, and reoperation for postoperative recurrence patients can still ob-rain better outcome.