93例AIDS患者并发贫血的临床分析

Clinical analysis on 93 cases of AIDS complicating anemia

目的研究获得性免疫缺陷综合征(AIDS)患者并发贫血的情况,探讨影响贫血发生的相关因素。方法回顾分析93例AIDS患者的临床资料,了解贫血发生率及特点,对贫血与总淋巴细胞数(TLC)、血红蛋白(Hb)与清蛋白(ALB)之间的关系进行分析。结果 93例AIDS患者中有61例并发贫血,贫血发生率为65.6%,轻、中、重度贫血分别占62.3%、26.2%、11.5%,大细胞、正细胞、小细胞性贫血各占8.2%、80.3%、11.5%。61例贫血患者中,27例(44.26%)为单纯贫血者,34例(55.74%)合并其他血细胞减少。贫血发生率随TLC减少逐渐增高,差异有统计学意义(P<0.05)。AIDS患者的Hb与ALB呈正相关(r=0.444,P<0.01)。结论 AIDS患者贫血的发生率较高,机会感染、免疫缺陷、营养状况与贫血发生相关。

Objective To investigate the condition of AIDS patients complicating anemia and the the factors related to anemia occurrence.Methods The clinical data of 93 AIDS patients were collected and analyzed for understanding the incidence of anemia and characteristics and analyzing the relationships between anemia with total lymphocyte count（TLC）,hemoglobin（Hb）concentration and serum albumin（ALB）.Results Among 93 AIDS patients,61 cases were complicated with anemia,the incidence rate of anemia was 65.6%,the mild,moderate and severe anemia accounted for 62.3%,26.2% and 11.5%respectively and macrocytic,normocytic and microcytic anemia accounted for 8.2%,80.3%and 11.5%respectively.Among 61 cases of anemia,27cases（44.26%）were simple anemia,34cases（55.74%）were combined with other blood cells decrease.The incidence rate of anemia was increased with the TLC decrease,the difference was statistically significant（P〈0.05）.Hb in AIDS patients was positively correlated with ALB（r=0.444,P〈0.01）.Conclusion The AIDS patients have relatively high incidence rate of anemia,the opportunistic infections,immunodeficiency and nutritional status are related with the anemia occurrence.