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NLRP3炎症小体与动脉粥样硬化的研究进展 被引量：2

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摘要 炎症小体是模式识别受体家族的一种多聚体蛋白复合物,作为分子平台来激活半胱天冬氨酸蛋白酶-1(caspase-1),从而调节促炎性细胞因子的释放。研究表明,NLRP3在动脉粥样硬化的发生、发展中起重要作用。该文就NLRP3炎症小体活化、调控机制及动脉粥样硬化中的相关研究进展作一综述。
作者 陈海燕 谭春燕 胡厚祥
机构地区 川北医学院附属医院心内科
出处 《国际心血管病杂志》 2015年第5期329-331,334,共4页 International Journal of Cardiovascular Disease
基金 国家自然科学基金项目(81070101) 四川省教育厅课题(12ZA060)
关键词 NLRP3 动脉粥样硬化 炎症小体
分类号 R543.5 [医药卫生—心血管疾病]
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参考文献24

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二级参考文献28

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国际心血管病杂志
2015年 第5期

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