2012年北京市密云县健康人群流行性腮腺炎抗体水平监测

Monitoring on antibody level of mumps among healthy population in Miyun county of Beijing,2012

目的了解2012年北京市密云县健康人群流行性腮腺炎抗体水平。方法按照地理位置、人口构成随机抽取密云县9个接种单位的10个行政村（居委会）为监测点。选择在当地连续居住6个月以上的20岁以下健康人群,分5个年龄组,共采集静脉血标本125份,且男、女性别比例在0.8～1.2之间。结果此次流行性腮腺炎抗体阳性率为59.20%;几何平均滴度（GMT）为47.07 RU/m L。不同年龄抗体阳性率差异有统计学意义（χ^2=40.025,P=0.000）;不同年龄GMT差异有统计学意义（F=14.724,P=0.000）。结论密云县1岁和5岁组健康人群流行性腮腺炎抗体阳性率、GMT保持在较高水平,而0岁及15岁以上人群抗体阳性率较低,流腮低发病水平使人群自然感染流腮病毒的机会减少,抗体随之降低,使得婴儿获得的母传抗体随之较低。

Objective To understand antibody level of mumps among healthy populations in Miyun of Beijing in 2012.Methods According to the geographical location and demographic data,10 administrative villages（ neighborhood communities）of 9 vaccination area county were randomly selected for monitoring in Miyun.Healthy people under the age of 20 who had been living in local continuously for 6 months or more were recruited and divided into 5 groups.Among them,the male to female ratio is 0.8 to 1.2.A total of 125 venous blood samples were collected.Results The positive rate of mumps antibody was 59.2%;The GMT was 40.07 RU / m L.The difference of antibody positive rate between different age groups was statistically significant（ χ^2= 40.025,P = 0.000）,the difference of GMT between different age groups was statistically significant（ F = 14.724,P =0.000）.Conclusion Mumps antibody positive rate and GMT among healthy population of 1 to 9 years old in Miyun county remains generally at a high level,but the antibody positive rate among 0 year and elder than 15 years old population were low.Low incidence of mumps reduced mumps infection and antibodies level among population,therefore reduced level of mumps antibody acquired from their mothers among babies.