肝癌患者手术部位感染病原菌和影响因素研究

目的研究肝癌患者手术部位感染的病原菌分布与影响因素,为针对性预防提供参考依据。方法选取285例肝癌患者,通过问卷调查方法收集患者临床资料,通过回归分析肝癌患者手术部位感染病原菌的分布及其影响因素。结果肝癌患者手术部位感染率为17.9%(51/285),感染病菌主要为革兰阴性菌。通过Logistic回归分析得出患者年龄大于65岁、营养不良、手术时间大于5 h以及糖尿病史均为肝癌患者手术部位感染的危险因素。结论肝癌患者手术部位感染率较大,主要为革兰阴性菌感染,并且疾病发展受多种因素影响。

Objective To study the pathogenic bacteria distribution of liver cancer patients with surgical site infection and acting factors, and provide reference basis for targeted prophylaxis. Methods The treatment of 285 patients with liver cancer, the patients clinical data collected through the questionnaire survey method, and using SPSS 18.0 software to process the collected relevant data, through descriptive statistics and Logistic regression to get the factors influencing the pathogenic bacteria of liver cancer patients with surgical site infection.Results The risk of surgical site infection for the liver cancer patients was 17.9% （51/285）, the main pathogens of gram-negative bacterium, accounting for 68.62% of all infections. We concluded through Logistic regression that patients older than 65 years old, malnutrition, operation timelonger than 5 h, history of diabetes will make liver cancer patients with increasing risk of surgical site infection. Conclusion Surgical site infection risk for the liver cancer patients is bigger, whcichis mainlycaused by gram-negative bacteria, and development is influenced by many factors.